Postmenopausal medication choises for breast cancer

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Some types of breast cancer are affected by hormones in the blood. ER-positive and PR-positive breast cancer cells have receptors proteins that attach to estrogen, which helps them grow. There are different ways to stop estrogen from attaching to these receptors.

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Hormone therapies may also be called endocrine therapies. The endocrine system in the body makes hormones. When these hormones attach to special proteins called hormone receptors, the cancer cells with these receptors grow.

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Jump to navigation. We reviewed the evidence concerning the effectiveness and safety of fulvestrant in prolonging time without further progression of cancer in women with advanced hormone -sensitive breast cancer. We found nine studies testing whether or not fulvestrant is superior to other treatment options.

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Hormones like estrogen and progesterone are chemicals produced by glands in the body. Normally, these hormones help regulate body cycles, like menstruation. However, sometimes these same hormones can cause cancer to grow. The pathologist will perform tests on the breast cancer cells to determine if they have receptors that feed on estrogen or progesterone, stimulating their growth.

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Hormones are substances that function as chemical messengers in the body. They affect the actions of cells and tissues at various locations in the body, often reaching their targets through the bloodstream. The hormones estrogen and progesterone are produced by the ovaries in premenopausal women and by some other tissues, including fat and skin, in both premenopausal and postmenopausal women and men.

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The menopause and breast cancer 2. What is the menopause? What are the common menopausal symptoms?

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Skip to Content. Use the menu to see other pages. This section explains the types of treatments that are the standard of care for early-stage and locally advanced breast cancer.

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Back to Breast cancer in women. You may have one of these treatments, or a combination. The type or combination of treatments you have will depend on how the cancer was diagnosed and the stage it's at.

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Tamoxifen is the oldest and most-prescribed selective estrogen receptor modulator SERM. Tamoxifen is approved by the U. Tamoxifen is available in two forms: a pill taken once a day brand name: Nolvadex or a liquid form brand name: Soltamox.

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A sweeping new analysis adds to the evidence that many women who take hormone therapy during menopause are more likely to develop breast cancer—and remain at higher risk of cancer for more than a decade after they stop taking the drugs. The longer women took the medicine, the more likely they were to develop breast cancer. Experts say the findings could shape how women and their health care providers decide how to manage symptoms of menopause.

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